Wouldn't we all like to know that!
Some thoughts, anyway:
- total return = income + capital gain - tax: you need to think about all of these
- use stocks & shares ISAs and share income with your spouse to reduce tax, if possible
- how much time do you want to spend? If no time, think about ETFs rather than expensive funds
- yield can help you identify risk: high yield = high risk
- diversify, but not too much
- you might be able to invest in some more pension, with tax benefits
- shop around for the best savings rates, ISAs
My own approach (described in detail on my website) is to focus on income but trying also not to lose money. I don't pay any tax on my 5-figure investment and savings income. My cash yield is an average of 4.7% and my investment portfolio yields around 5.5%. Capital gain this year was huge - but this is exceptional.
http://www.the-diy-income-investor.com/